Pure Peptides Australia
CJC-1295 (DAC) 5mg โ Research Peptide | Pure Peptides Australia
CJC-1295 (DAC) 5mg โ Research Peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Growth hormone research compound
CJC-1295 DAC (5mg): Long-Acting GHRH Analogue for Sustained GH Research
CJC-1295 with DAC is a modified 29-amino-acid GHRH fragment carrying a Drug Affinity Complex, a maleimide-based tail that covalently binds serum albumin after administration. That bond turns a peptide that would clear in minutes into one that circulates for about a week, producing sustained elevation of growth hormone and IGF-1 rather than a single pulse. Developed by ConjuChem in the early 2000s, it is the compound for research questions about continuous rather than pulsatile GHRH exposure. Searched as cjc 1295 dac australia, cjc-1295 with dac, cjc dac, cjc 1295 australia and dac vs no dac.
Pure Peptides Australia holds CJC-1295 DAC in Sydney stock as a 5mg lyophilised vial, Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery Australia-wide.
- CJC-1295 DAC
- CJC 1295 with DAC
- CJC DAC
- Drug Affinity Complex
- Mod GRF 1-29 + DAC
- Long-acting GHRH
DAC vs No DAC
The peptide is the same in both: Mod GRF 1-29, four substitutions on the Sermorelin backbone that resist enzymatic breakdown. The DAC tail is the only difference, and it changes the research question entirely. No DAC gives a 30-minute pulse and is used in prime-and-pulse pairing with a GHRP, which is what the CJC-1295 + Ipamorelin blend is built on. DAC gives a week of continuous GHRH tone, raising baseline GH and IGF-1 across the whole period. One is for studying pulses, the other for studying sustained exposure; they are not substitutes.
Key research areas
Sustained GH and IGF-1
Phase 1 and 2 work reported GH elevated for six days and IGF-1 for up to 28 days after a single administration (Teichman et al., JCEM 2006).
Albumin conjugation
The DAC platform itself: covalent binding to circulating albumin as a half-life extension strategy, studied across several peptide classes.
Pulsatility preservation
Whether continuous GHRH tone preserves or blunts natural GH pulses; the 2006 data reported pulsatility maintained with amplitude increased.
Body composition
Lean-mass and fat-mass endpoints over multi-week exposure in animal models.
Receptor desensitisation
Continuous agonism as a model for GHRH receptor downregulation, and the dosing interval at which it occurs.
Comparison with Tesamorelin
Two routes to a longer-acting GHRH: DAC's albumin binding versus Tesamorelin's N-terminal cap and daily administration.
How CJC-1295 DAC works
After administration the DAC maleimide group reacts with the free thiol on cysteine-34 of albumin, forming a stable covalent bond. Bound to albumin, the peptide is protected from peptidases and renal clearance and takes on albumin's six to eight day half-life. Throughout that period it binds GHRH receptors on somatotrophs, raising the baseline from which natural pulses rise. Published data suggest pulses remain but sit on a higher floor, with IGF-1 rising two to three fold at higher exposures.
Specifications
| Compound | CJC-1295 with DAC |
| Also known as | CJC-1295 DAC, CJC DAC, Mod GRF 1-29 with Drug Affinity Complex, long-acting GHRH analogue |
| CAS number | 446262-90-4 |
| Molecular formula | C165H269N47O46 |
| Molecular weight | ~3647.3 g/mol |
| Structure | 29 amino acids with four substitutions plus a maleimidoproprionic acid DAC tail |
| Half-life (published) | 6 to 8 days (albumin-bound) |
| Category | Growth hormone research |
| Purity | โฅ99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial size | 5mg |
| Storage (lyophilised) | -20ยฐC, protect from light, avoid freeze-thaw |
| Storage (reconstituted) | 2 to 8ยฐC, use within 28 days |
| Reconstitution | Bacteriostatic water |
Pricing in Australia
$99.99 for 5mg, $20.00 per mg
Because DAC lasts a week, published models use it once or twice weekly at 1 to 2mg, so a 5mg vial covers three to five weeks of a single arm. The No DAC blend ($129.99, 10mg) is the alternative for pulse research.
Reconstitution
Wipe the stopper, add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake. Refrigerate at 2 to 8ยฐC and use within 28 days.
| Water added | Concentration | 1mg on a U-100 syringe | 2mg on a U-100 syringe |
| 1mL | 5mg/mL | 20 units | 40 units |
| 2mL | 2.5mg/mL | 40 units | 80 units |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, mass-spec identity against 3647 g/mol confirming the DAC tail is present, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
$89.99. A GHRP to layer pulses on the DAC baseline.
$129.99. The pulse-research alternative.
From $89.99. The other long-acting GHRH route.
10mL $29.99, 3mL $14.99. Required for reconstitution.
CJC-1295 DAC Australia FAQ
What is CJC-1295 DAC?
A modified GHRH 1-29 fragment with a Drug Affinity Complex tail that binds albumin, extending its half-life to about a week and producing sustained GH and IGF-1 elevation rather than a single pulse.
What is the difference between DAC and No DAC?
Same peptide, different tail. No DAC clears in 30 minutes and is used for pulse pairing with a GHRP. DAC circulates for a week and is used for sustained-exposure research. They answer different questions.
How does CJC-1295 DAC work?
The DAC group bonds covalently to albumin in circulation, shielding the peptide from clearance. Bound, it stimulates GHRH receptors continuously, raising baseline GH and IGF-1 while natural pulses continue on top.
What does the research show?
A single administration raised GH for six days and IGF-1 for up to 28 days in the 2006 clinical work, with pulsatility preserved and amplitude increased. Later work examined body composition over multi-week exposure.
CJC-1295 DAC vs Tesamorelin?
Both extend GHRH activity. DAC does it by albumin binding for a week; Tesamorelin by an N-terminal cap with daily administration and a much larger clinical dataset, chiefly on visceral fat.
Can I buy CJC-1295 at Chemist Warehouse in Australia?
No. CJC-1295 is not a registered medicine and no Australian pharmacy stocks it. It is available only as a research-grade lyophilised vial.
How do you reconstitute CJC-1295 DAC?
Add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake, refrigerate at 2 to 8ยฐC and use within 28 days. 1mL gives 5mg/mL, so 1mg is 20 units.
Is CJC-1295 DAC available in Australia?
As a research compound, yes: Pure Peptides Australia holds the 5mg vial in Sydney with same-day dispatch. As a medicine, no. As of October 2026 it is not TGA approved.
Where can I buy CJC-1295 DAC in Australia?
From this page. Check out with card, PayID, Osko or bank transfer and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does CJC-1295 DAC cost in Australia?
$99.99 for the 5mg vial, $20.00 per mg. No surcharge on PayID, Osko or bank transfer.
Is CJC-1295 DAC legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
