Pure Peptides Australia
Melanotan II 10mg โ Research Peptide | Pure Peptides Australia
Melanotan II 10mg โ Research Peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Dermal research compound
Melanotan II (10mg): Cyclic Melanocortin Agonist for Pigmentation and Melanocortin Research
Melanotan II, MT2, is a seven-amino-acid cyclic analogue of alpha-melanocyte-stimulating hormone developed at the University of Arizona in the 1980s. The ring structure makes it more stable and more potent than the native hormone, and unlike its linear cousin Melanotan I it activates four melanocortin receptors, MC1R, MC3R, MC4R and MC5R, which is why it is studied for pigmentation, appetite and sexual function together. It is the most searched melanocortin peptide in Australia. Searched as melanotan 2 australia, mt2 australia, melanotan ii, mt-2 peptide and tanning peptide.
Pure Peptides Australia holds Melanotan II in Sydney stock as a 10mg lyophilised vial, Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery Australia-wide. A Starter Kit adds water and syringes.
- MT2
- MT-2
- Melanotan 2
- Melanotan II
- Cyclic alpha-MSH analogue
- Bremelanotide precursor
MT2 vs MT1
The two Melanotans differ in shape and reach. MT1 is linear and selective for MC1R, so its research is pigmentation and photoprotection only. MT2 is cyclic and non-selective: MC1R gives the pigmentation, MC4R gives the appetite suppression and sexual-function effects, and MC4R is also the source of the nausea and flushing reported in early studies. MT2 is the compound for broad melanocortin research; MT1 for a clean pigmentation model. PT-141 is MT2's own metabolite, isolated because it kept the MC4R effects without the pigmentation.
Key research areas
Melanogenesis
MC1R activation raises cAMP in melanocytes and drives eumelanin synthesis; the first and best-established MT2 endpoint (Dorr et al., Life Sciences 1996).
Sexual function
The University of Arizona trials that reported erectile responses (Wessells et al., Journal of Urology 1998) led directly to PT-141's development.
Appetite and energy balance
MC4R is the central appetite receptor; MT2 is a standard tool for MC4R agonism in feeding and body-weight models.
Photoprotection
Eumelanin absorbs UV and scavenges radicals; studied for reducing UV-induced DNA damage.
Receptor pharmacology
MT2 is the reference non-selective agonist used to characterise selective compounds against.
Inflammation
Melanocortin receptors on immune cells; alpha-MSH analogues studied for damping inflammatory signalling.
How Melanotan II works
The lactam bridge that closes MT2's ring protects it from enzymatic breakdown and locks it into the shape melanocortin receptors recognise, giving it potency in the nanomolar range across MC1R, MC3R, MC4R and MC5R. At MC1R on melanocytes it raises cAMP, activates MITF and shifts melanin production toward eumelanin. At MC4R in the hypothalamus it suppresses feeding and, through separate spinal and central circuits, produces the sexual-function effects. Its half-life is a few hours, longer than native alpha-MSH, and it is light-sensitive in solution.
Specifications
| Compound | Melanotan II (MT2) |
| Also known as | MT-2, Melanotan 2, melanotan two, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, tanning peptide |
| CAS number | 121062-08-6 |
| Molecular formula | C50H69N15O9 |
| Molecular weight | 1024.2 g/mol |
| Structure | 7 amino acids, cyclic (lactam bridge), acetylated N-terminus |
| Category | Dermal research |
| Purity | โฅ99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial size | 10mg |
| Storage (lyophilised) | -20ยฐC, protect from light, avoid freeze-thaw |
| Storage (reconstituted) | 2 to 8ยฐC, dark, use within 28 days |
| Reconstitution | Bacteriostatic water |
Pricing in Australia
$79.99 for 10mg, $8.00 per mg
MT2 is studied in fractions of a milligram, so a 10mg vial yields forty 250mcg draws. The Melanotan II Starter Kit ($109.99) adds bacteriostatic water and syringes. Melanotan I is $69.99 for the same 10mg.
Reconstitution
Wipe the stopper, add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake. Keep the reconstituted vial wrapped or in a dark fridge at 2 to 8ยฐC; melanocortin peptides degrade in light. Use within 28 days.
| Water added | Concentration | 250mcg on a U-100 syringe | 500mcg on a U-100 syringe |
| 1mL | 10mg/mL | 2.5 units | 5 units |
| 2mL | 5mg/mL | 5 units | 10 units |
| 4mL | 2.5mg/mL | 10 units | 20 units |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, mass-spec identity against 1024 g/mol, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
$109.99. 10mg with water, syringes and swabs.
$69.99. The selective MC1R comparison.
$69.99. MT2's metabolite, MC4R effects without pigmentation.
10mL $29.99, 3mL $14.99. Required for reconstitution.
Melanotan II Australia FAQ
What is MT2?
MT2 is Melanotan II, a cyclic seven-amino-acid analogue of alpha-MSH that activates four melanocortin receptors. It is studied for pigmentation, appetite and sexual function, and is the most searched melanocortin peptide in Australia.
What is Melanotan II also known as?
MT2, MT-2, Melanotan 2, melanotan two and, informally, the tanning peptide. It is the parent compound of PT-141 (bremelanotide).
Melanotan II vs Melanotan I: what is the difference?
MT1 is linear and selective for MC1R: pigmentation only. MT2 is cyclic and activates MC1R, MC3R, MC4R and MC5R: pigmentation plus appetite and sexual-function effects, with MC4R-related nausea and flushing in early studies.
How does Melanotan II work?
Its lactam ring locks it into the shape melanocortin receptors recognise. At MC1R it drives eumelanin; at MC4R it suppresses feeding and produces sexual-function effects through central circuits. Half-life is a few hours.
What does the research show?
Increased eumelanin and photoprotection in melanocyte and animal models, erectile responses in the 1998 University of Arizona trials that led to PT-141, and MC4R-driven appetite suppression in feeding models.
Can I buy Melanotan II at Chemist Warehouse in Australia?
No. Melanotan II is not a registered medicine anywhere and is not stocked by any Australian pharmacy. It is available only as a research-grade lyophilised vial.
How do you reconstitute Melanotan II?
Add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake, keep it dark, refrigerate at 2 to 8ยฐC and use within 28 days. 2mL gives 5mg/mL, so 250mcg is 5 units on a U-100 syringe.
How should Melanotan II be stored?
Lyophilised at -20ยฐC, away from light. Reconstituted in a dark fridge at 2 to 8ยฐC and used within 28 days.
Is Melanotan II available in Australia?
As a research compound, yes: Pure Peptides Australia holds the 10mg vial in Sydney with same-day dispatch. As a medicine, no. As of October 2026 it is not TGA approved.
Where can I buy Melanotan II in Australia?
From this page. Check out with card, PayID, Osko or bank transfer and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does Melanotan II cost in Australia?
$79.99 for the 10mg vial, $8.00 per mg, or $109.99 for the Starter Kit with water and syringes. No surcharge on PayID, Osko or bank transfer.
Is Melanotan II legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
