Pure Peptides Australia
Sermorelin 5mg β Research Peptide | Pure Peptides Australia
Sermorelin 5mg β Research Peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Growth hormone research compound
Sermorelin (5mg and 10mg): The Reference GHRH 1-29 Fragment
Sermorelin is the first 29 amino acids of growth hormone releasing hormone, the shortest fragment that retains full activity at the GHRH receptor. It was the first GHRH analogue to reach clinical use, approved in the 1990s for growth hormone deficiency in children and as a diagnostic agent, and it remains the reference compound against which every modified GHRH analogue is measured. Searched as sermorelin australia, sermorelin peptide, sermorelin acetate, ghrh 1-29 and sermorelin vs ipamorelin.
Pure Peptides Australia holds Sermorelin in Sydney stock in 5mg and 10mg vials, Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery Australia-wide.
- Sermorelin
- GHRH 1-29
- GRF 1-29
- Sermorelin acetate
- Geref (brand)
- Sermoralin
Sermorelin, CJC-1295 and Tesamorelin
All three act on the same GHRH receptor; they differ in how long they last. Sermorelin is unmodified and cleared by DPP-4 within minutes, producing a short physiological pulse. CJC-1295 adds four substitutions (Mod GRF 1-29) and, in the DAC form, an albumin-binding tail that extends it to about a week. Tesamorelin keeps all 44 amino acids with an N-terminal cap and has the largest clinical dataset. Sermorelin is the choice when the research question needs the natural fragment and the shortest pulse.
Key research areas
GHRH receptor pharmacology
The reference agonist for characterising pituitary somatotroph response and receptor desensitisation.
Pulsatile GH release
Studied for restoring the amplitude of natural GH pulses while preserving negative feedback through somatostatin and IGF-1.
Diagnostic stimulation
Historically used as a GH stimulation test agent, the basis for much of its human pharmacokinetic data.
GHRP pairing
Paired with Ipamorelin in prime-and-pulse designs, the same logic as the CJC-1295 pairing with a shorter GHRH component.
Sleep architecture
Studied for slow-wave sleep and the nocturnal GH pulse in ageing models.
Body composition
Lean-mass and fat-mass endpoints in older adults in early clinical work (Vittone et al., Metabolism 1997).
How Sermorelin works
Sermorelin binds the GHRH receptor on pituitary somatotrophs, raising cAMP and triggering synthesis and release of growth hormone. Because it is the natural fragment, the pituitary's own feedback stays intact: rising IGF-1 and somatostatin shut the pulse down as they would after endogenous GHRH. Plasma half-life is 10 to 20 minutes, so its effect is a single sharp pulse rather than sustained elevation, which some research designs prefer precisely because it mimics physiology.
Specifications
| Compound | Sermorelin (GHRH 1-29) |
| Also known as | Sermorelin acetate, GRF 1-29, GHRH 1-29 NH2, Geref (brand), sermoralin (misspelling) |
| CAS number | 86168-78-7 |
| Molecular formula | C149H246N44O42S |
| Molecular weight | 3357.9 g/mol |
| Structure | 29 amino acids, amidated C-terminus |
| Half-life (published) | 10 to 20 minutes |
| Category | Growth hormone research |
| Purity | β₯99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial sizes | 5mg, 10mg |
| Storage (lyophilised) | -20Β°C, protect from light, avoid freeze-thaw |
| Storage (reconstituted) | 2 to 8Β°C, use within 28 days |
| Reconstitution | Bacteriostatic water |
Sizes and pricing in Australia
Two sizes, the 10mg at a lower per-mg cost
| Vial | Price | Per mg | Yields at 200mcg |
| 5mg | $89.99 | $18.00 | 25 draws |
| 10mg | $129.99 | $13.00 | 50 draws |
Sermorelin protocols run daily, often at night, so the 10mg suits anything longer than a month.
Reconstitution
Wipe the stopper, add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake. Refrigerate at 2 to 8Β°C and use within 28 days.
| Vial | Water added | Concentration | 200mcg on a U-100 syringe |
| 5mg | 2mL | 2.5mg/mL | 8 units |
| 10mg | 2mL | 5mg/mL | 4 units |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, mass-spec identity against 3358 g/mol, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
$89.99. The GHRP for prime-and-pulse pairing.
$99.99. The long-acting GHRH comparison.
From $89.99. The full-length capped GHRH.
10mL $29.99, 3mL $14.99. Required for reconstitution.
Sermorelin Australia FAQ
What is Sermorelin?
The first 29 amino acids of growth hormone releasing hormone, the shortest fully active fragment. It was the first GHRH analogue in clinical use and remains the reference compound for GHRH research.
Sermorelin vs CJC-1295?
Same 29-amino-acid backbone. CJC-1295 adds substitutions that resist breakdown and, with DAC, an albumin tail that extends it to about a week. Sermorelin is the unmodified fragment with a 10 to 20 minute half-life and a single physiological pulse.
Sermorelin vs Ipamorelin?
Different receptors. Sermorelin acts on the GHRH receptor to prime the pituitary; Ipamorelin acts on the ghrelin receptor to trigger release. They are paired, not swapped.
How does Sermorelin work?
It binds the GHRH receptor on somatotrophs, raising cAMP and triggering GH synthesis and release, with the pituitary's own feedback intact.
What does the research show?
Restored GH pulse amplitude with preserved feedback, diagnostic utility in GH stimulation testing, and body-composition changes in older adults in early clinical work.
Can I buy Sermorelin at Chemist Warehouse in Australia?
No. Sermorelin is not registered on the ARTG and no Australian pharmacy stocks it. It is available only as a research-grade lyophilised vial.
How do you reconstitute Sermorelin?
Add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake, refrigerate at 2 to 8Β°C and use within 28 days. 2mL into the 10mg gives 5mg/mL, so 200mcg is 4 units.
Is Sermorelin available in Australia?
As a research compound, yes: Pure Peptides Australia holds 5mg and 10mg vials in Sydney with same-day dispatch. As a medicine, no. As of October 2026 it is not TGA approved.
Where can I buy Sermorelin in Australia?
From this page. Choose a size, check out with card, PayID, Osko or bank transfer, and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does Sermorelin cost in Australia?
$89.99 for 5mg ($18.00 per mg) or $129.99 for 10mg ($13.00 per mg). No surcharge on PayID, Osko or bank transfer.
Is Sermorelin legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
