Pure Peptides Australia
Tesamorelin 10mg β Research Peptide | Pure Peptides Australia
Tesamorelin 10mg β Research Peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Growth hormone research compound
Tesamorelin (5mg to 20mg): Stabilised GHRH Analogue Research Peptide
Tesamorelin is a 44-amino-acid synthetic analogue of growth hormone releasing hormone (GHRH) with a trans-3-hexenoic acid group on the N-terminus that protects it from enzymatic breakdown. It is the GHRH analogue with the deepest clinical record, developed by Theratechnologies and studied for more than a decade, and it is the compound Australian researchers search for most after the growth hormone secretagogues themselves. Searched as tesamorelin australia, tesamorelin peptide, TH9507 and its brand name Egrifta.
Pure Peptides Australia holds Tesamorelin in Sydney stock in 5mg, 10mg and 20mg vials, each lyophilised and Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery Australia-wide.
- Tesamorelin
- TH9507
- GHRH analogue
- GHRH 1-44
- Egrifta (brand)
- Tesamoreline
Where it sits in the GH family
The growth hormone peptides split into two groups. GHRH analogues, including Tesamorelin, Sermorelin and CJC-1295, act on the pituitary's GHRH receptor to prime a growth hormone pulse. Ghrelin-receptor agonists such as Ipamorelin trigger the pulse itself. Tesamorelin is the GHRH analogue with the strongest published data, most of it on visceral fat rather than muscle, which is what sets it apart from Sermorelin.
Key research areas
Visceral adipose tissue
Two 26-week Phase 3 trials (Falutz et al., NEJM 2007 and JCEM 2010, n=816) reported roughly 15% to 18% reduction in visceral fat by CT scan against placebo, the endpoint Tesamorelin is best known for.
Hepatic fat
A 12-month randomised trial (Stanley et al., Lancet HIV 2019) reported reduced liver fat and less progression of fibrosis, tying the compound to NAFLD research.
IGF-1 and GH axis
Studied for sustained increases in IGF-1 through pulsatile GH release rather than direct GH administration, preserving negative feedback.
Cognition
A 20-week trial in older adults (Baker et al., Archives of Neurology 2012) examined executive function and verbal memory, an unusual endpoint for a GHRH analogue.
Body composition
Studied for lean-mass preservation alongside fat reduction, with trunk fat and waist circumference as secondary endpoints across the Phase 3 programme.
Comparison with Sermorelin
Same receptor, but Tesamorelin's N-terminal modification gives a longer half-life and a much larger published dataset. Sermorelin remains the unmodified reference fragment.
How Tesamorelin works
Native GHRH is broken down within minutes by dipeptidyl peptidase-4. Tesamorelin keeps the full 44-amino-acid sequence but caps the N-terminus with a hexenoyl group, which blocks that cleavage and extends the plasma half-life to around 26 to 38 minutes, long enough to drive a physiological GH pulse from the pituitary. Because the pulse comes from the pituitary rather than from injected GH, IGF-1 rises while the feedback loop stays intact. Research models pair it with a ghrelin-receptor agonist such as Ipamorelin, the same prime-and-pulse logic as the CJC-1295 and Ipamorelin combination.
One practical note: Tesamorelin is a large, hydrophobic peptide and can be slow to dissolve. Bacteriostatic water added gently, with the vial left to stand rather than agitated, is the reliable method; other diluents may not fully dissolve it.
Specifications
| Compound | Tesamorelin (TH9507) |
| Also known as | Tesamorelin acetate, GHRH 1-44 analogue, trans-3-hexenoyl GHRH, Egrifta (brand name), tesamoreline |
| CAS number | 218949-48-5 |
| Molecular formula | C221H366N72O67S |
| Molecular weight | 5135.9 g/mol |
| Structure | 44 amino acids, N-terminal trans-3-hexenoic acid |
| Half-life (published) | 26 to 38 minutes |
| Category | Growth hormone research |
| Purity | β₯99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial sizes | 5mg, 10mg, 20mg |
| Storage (lyophilised) | -20Β°C, protect from light, avoid freeze-thaw |
| Storage (reconstituted) | 2 to 8Β°C, use within 28 days |
| Reconstitution | Bacteriostatic water, added slowly, no agitation |
Sizes and pricing in Australia
Three vial sizes, price per mg falling with size
| Vial | Price | Per mg | Yields |
| 5mg | $89.99 | $18.00 | Five 1mg aliquots |
| 10mg | $139.99 | $14.00 | Ten 1mg or five 2mg |
| 20mg | $219.99 | $11.00 | Twenty 1mg or ten 2mg |
Published Tesamorelin protocols run daily rather than weekly, so a 10mg vial covers a shorter window than the same mass of a weekly compound. The 20mg suits a full 26-week-style arm; the 5mg suits a batch check or a pairing study alongside Ipamorelin.
Reconstitution
Let the vial reach room temperature. Wipe the stopper, draw bacteriostatic water and run it slowly down the inside wall. Tesamorelin dissolves slowly; leave the vial to stand and tilt gently rather than swirling hard, and never shake. Refrigerate at 2 to 8Β°C and use within 28 days.
| Vial | Water added | Concentration | 1mg on a U-100 syringe |
| 5mg | 1mL | 5mg/mL | 20 units |
| 10mg | 2mL | 5mg/mL | 20 units |
| 20mg | 2mL | 10mg/mL | 10 units |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, mass-spec identity against 5136 g/mol, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
$89.99. The ghrelin-receptor agonist most often paired with a GHRH analogue.
10mL $29.99, 3mL $14.99. The recommended diluent for Tesamorelin.
From $89.99. The unmodified GHRH 1-29 reference.
$129.99. The prime-and-pulse pairing pre-mixed.
Tesamorelin Australia FAQ
What is Tesamorelin?
A synthetic 44-amino-acid analogue of growth hormone releasing hormone with an N-terminal hexenoyl group that protects it from enzymatic breakdown. It stimulates the pituitary to release growth hormone in a physiological pulse and is the GHRH analogue with the largest published trial record.
What is Tesamorelin also known as?
TH9507, tesamorelin acetate, trans-3-hexenoyl GHRH 1-44 and, as an approved product overseas, Egrifta. It is sometimes misspelled tesamoreline or tesamorlin.
How does Tesamorelin work?
It binds the GHRH receptor on pituitary somatotrophs and triggers growth hormone release. Because the hexenoyl cap blocks DPP-4 cleavage, it survives long enough in plasma to produce a meaningful pulse, raising IGF-1 while leaving the GH feedback loop intact.
What does the research show?
Two 26-week Phase 3 trials reported 15% to 18% visceral fat reduction by CT scan. A 12-month trial reported reduced liver fat and less fibrosis progression. A 20-week trial in older adults examined cognitive endpoints. These describe controlled trials of a pharmaceutical-grade product.
Tesamorelin vs Sermorelin: what is the difference?
Both are GHRH analogues acting on the same receptor. Sermorelin is the unmodified first 29 amino acids of GHRH with a half-life of minutes. Tesamorelin keeps all 44 amino acids and adds the hexenoyl cap, giving a longer half-life and a far larger body of published data, most of it on visceral fat.
Can I buy Tesamorelin at Chemist Warehouse in Australia?
No. Tesamorelin is not registered on the ARTG and is not stocked by Chemist Warehouse or any Australian pharmacy. It is available in Australia only as a research-grade lyophilised vial.
Why is Tesamorelin slow to dissolve?
It is a large, relatively hydrophobic peptide. Add bacteriostatic water slowly down the vial wall and let the vial stand; tilt gently rather than swirling hard. It will clear. Other diluents may not fully dissolve it.
How do you reconstitute Tesamorelin?
Bring the vial to room temperature, swab the stopper, add bacteriostatic water slowly down the inside wall, let it stand until clear, never shake, then refrigerate at 2 to 8Β°C and use within 28 days. A 10mg vial with 2mL gives 5mg/mL, so 1mg is 20 units.
How should Tesamorelin be stored?
Lyophilised at -20Β°C, away from light, without repeated freeze-thaw. Reconstituted at 2 to 8Β°C and used within 28 days.
Is Tesamorelin available in Australia?
As a research compound, yes: Pure Peptides Australia holds 5mg, 10mg and 20mg vials in Sydney with same-day dispatch. As a medicine, no. As of October 2026 it is not TGA approved and not on the ARTG.
Where can I buy Tesamorelin in Australia?
From this page. Choose a size, check out with card, PayID, Osko or bank transfer, and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does Tesamorelin cost in Australia?
$89.99 for 5mg, $139.99 for 10mg and $219.99 for 20mg, which is $18.00 down to $11.00 per mg. No surcharge on PayID, Osko or bank transfer.
Is Tesamorelin legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
