Pure Peptides Australia
NAD+ 500mg โ Research Peptide | Pure Peptides Australia
NAD+ 500mg โ Research Peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Longevity research compound
NAD+ (500mg): Nicotinamide Adenine Dinucleotide for Cellular Energy and Ageing Research
NAD+ is not a peptide but a coenzyme, the molecule every cell uses to move electrons in energy metabolism and the substrate that sirtuins and PARP enzymes consume to repair DNA and regulate ageing. Cellular NAD+ levels fall by roughly half between young adulthood and old age, which is why it is one of the most studied molecules in longevity research and one of the most searched in Australia. Searched as nad+ australia, nad australia, nad plus, nad+ 500mg and nad injection research.
Pure Peptides Australia holds NAD+ in Sydney stock as a 500mg lyophilised vial, Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery Australia-wide.
- NAD+
- NAD plus
- Nicotinamide adenine dinucleotide
- Beta-NAD
- Coenzyme 1
- NAD 500mg
Why the raw molecule rather than a precursor
Most NAD+ research in supplements uses precursors, NMN or NR, which cells convert to NAD+ through the salvage pathway. The 500mg research vial supplies NAD+ itself, which lets a model bypass the conversion step and the enzymes that rate-limit it. That matters for research on tissues where the salvage pathway is impaired, and for direct comparison of precursor versus end-product delivery. The trade-off is stability: NAD+ in solution degrades faster than the precursors, which is why it ships lyophilised and is used within days of reconstitution.
Key research areas
Sirtuin activation
SIRT1 to SIRT7 consume NAD+ to deacetylate proteins that control metabolism, stress response and lifespan (Imai and Guarente, Trends in Cell Biology 2014).
Mitochondrial function
NAD+/NADH ratio drives oxidative phosphorylation; restoring it in aged tissue is studied for ATP output and mitochondrial biogenesis.
DNA repair
PARP1 consumes NAD+ to repair DNA breaks; chronic damage depletes the pool, a proposed link between DNA damage and ageing.
Neuroprotection
Axonal NAD+ depletion via SARM1 is studied in neurodegeneration; NAD+ supply is examined for axon survival.
Metabolic disease models
Diet-induced obesity and insulin-resistance models examine NAD+ restoration for glucose handling and liver fat.
Precursor comparison
Direct NAD+ versus NMN and NR delivery, and the role of the NAMPT salvage enzyme that declines with age.
How NAD+ works
NAD+ cycles between two states: it accepts electrons to become NADH in glycolysis and the citric acid cycle, then hands them to the mitochondrial electron transport chain to make ATP. Separately, it is consumed as a substrate by sirtuins, PARPs and CD38. Those consumers, especially CD38, rise with age and drain the pool faster than the salvage pathway can refill it. Research that supplies NAD+ directly examines whether restoring the pool restores the downstream sirtuin and mitochondrial functions. NAD+ does not cross cell membranes easily; how much enters cells intact versus being broken down to precursors and rebuilt inside is itself an active research question.
Specifications
| Compound | NAD+ (beta-nicotinamide adenine dinucleotide) |
| Also known as | NAD plus, NAD, beta-NAD, coenzyme 1, diphosphopyridine nucleotide (DPN) |
| CAS number | 53-84-9 |
| Molecular formula | C21H27N7O14P2 |
| Molecular weight | 663.4 g/mol |
| Category | Longevity research (coenzyme, non-peptide) |
| Purity | โฅ99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial size | 500mg |
| Storage (lyophilised) | -20ยฐC, protect from light and moisture |
| Storage (reconstituted) | 2 to 8ยฐC, use within 7 days; NAD+ degrades faster in solution than peptides |
| Reconstitution | Bacteriostatic water |
Pricing in Australia
$129.99 for 500mg, $0.26 per mg
NAD+ is used in far larger amounts than peptides, typically tens to hundreds of milligrams per draw, so a 500mg vial is one to ten draws depending on the model. Because reconstituted NAD+ is used within a week, researchers running longer designs reconstitute in portions rather than the whole vial at once.
Reconstitution
NAD+ is a large fill and needs more water than a peptide vial. Wipe the stopper, add bacteriostatic water slowly, swirl gently until fully dissolved, never shake. The solution is slightly acidic and should be used within 7 days, refrigerated at 2 to 8ยฐC and kept from light.
| Water added | Concentration | 50mg on a U-100 syringe | 100mg on a U-100 syringe |
| 5mL | 100mg/mL | 50 units | 100 units (1mL) |
| 10mL | 50mg/mL | 100 units (1mL) | 2mL |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, identity against 663 g/mol, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
$29.99. A 500mg vial needs the full 10mL.
From $99.99. Mitochondrial signalling alongside NAD+ supply.
From $79.99. The telomere arm of longevity research.
$159.99. The cell's main antioxidant, often paired with NAD+.
NAD+ Australia FAQ
What is NAD+?
Nicotinamide adenine dinucleotide, the coenzyme every cell uses to carry electrons in energy metabolism and the substrate sirtuins and PARPs consume for DNA repair and ageing regulation. Levels fall by about half over adult life.
Is NAD+ a peptide?
No. It is a dinucleotide coenzyme. It is stocked alongside research peptides because it is reconstituted and handled the same way and is studied in the same longevity models.
NAD+ vs NMN vs NR?
NMN and NR are precursors that cells convert to NAD+ through the salvage pathway. The 500mg vial supplies NAD+ itself, bypassing that conversion, which is useful for research on tissues where the pathway is impaired and for direct comparison of delivery routes.
How does NAD+ work?
It cycles between NAD+ and NADH to move electrons to the mitochondria for ATP, and it is consumed by sirtuins, PARPs and CD38. Those consumers rise with age and drain the pool faster than it refills.
What does the research show?
In animal models, restoring NAD+ improves mitochondrial function, insulin sensitivity and some markers of ageing, and supports axon survival in neurodegeneration models. Human data are mostly on precursors; direct NAD+ research is the newer field.
Can I buy NAD+ at Chemist Warehouse in Australia?
Pharmacies sell NMN and NR precursor supplements. Research-grade lyophilised NAD+ in a 500mg vial is a different product, not a registered medicine, and is not stocked by pharmacies.
How do you reconstitute NAD+?
Add 5 to 10mL of bacteriostatic water slowly, swirl gently until fully dissolved, never shake. Refrigerate at 2 to 8ยฐC, keep from light and use within 7 days. 10mL gives 50mg/mL, so 50mg is 100 units (1mL).
Why only 7 days once reconstituted?
NAD+ hydrolyses in solution faster than peptides do, especially at neutral pH and room temperature. Reconstitute in portions if the design runs longer than a week.
Is NAD+ available in Australia?
As a research compound, yes: Pure Peptides Australia holds the 500mg vial in Sydney with same-day dispatch. As a medicine, no. As of October 2026 injectable NAD+ is not TGA approved.
Where can I buy NAD+ in Australia?
From this page. Check out with card, PayID, Osko or bank transfer and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does NAD+ cost in Australia?
$129.99 for the 500mg vial, $0.26 per mg. No surcharge on PayID, Osko or bank transfer.
Is NAD+ legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use in this form and is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
