Pure Peptides Australia
DSIP 10mg - Research Peptide | Pure Peptides Australia
DSIP 10mg - Research Peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Sleep research compound
DSIP (10mg): Delta Sleep-Inducing Peptide for Sleep Architecture and Stress Research
DSIP is a nine-amino-acid peptide first isolated in 1977 from the cerebral venous blood of rabbits in induced slow-wave sleep, which is where its name comes from: it was the factor that carried the sleep state from one animal to another. Nearly fifty years on it remains the reference peptide for delta-wave sleep research, and it is also studied for stress-hormone regulation, chronic pain and withdrawal states. Searched as dsip australia, dsip peptide, delta sleep inducing peptide, dsip sleep and dsip 10mg.
Pure Peptides Australia holds DSIP in Sydney stock as a 10mg lyophilised vial, Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery Australia-wide.
- DSIP
- Delta sleep-inducing peptide
- Emideltide
- WAGGDASGE
- DSIP peptide
- Sleep peptide
What it is and is not
DSIP is not a sedative. In the original and later work it did not knock animals out; it shifted the balance of sleep stages toward delta (slow-wave) sleep, the deepest stage and the one in which growth hormone pulses and memory consolidation occur. That distinction is why it is studied alongside the growth hormone secretagogues and the nootropic peptides rather than with hypnotics. It has also been studied for normalising cortisol rhythm, which is the link to its stress and withdrawal research.
Key research areas
Slow-wave sleep
Increased delta-wave sleep and improved sleep efficiency in animal models and small human studies (Schoenenberger, European Neurology 1984 review).
Cortisol and stress
Reported to reduce basal cortisol and blunt stress-induced ACTH, with effects on the hypothalamic-pituitary-adrenal axis.
Withdrawal states
Russian and European studies examined alcohol and opioid withdrawal symptoms, the basis of the emideltide name.
Chronic pain
Small studies in chronic pain and migraine reported reduced pain scores, via central rather than opioid mechanisms.
GH and LH secretion
Studied for effects on pituitary hormone pulses that ride on slow-wave sleep.
Antioxidant and neuroprotection
Studied for reduced oxidative damage in stress and hypoxia models.
How DSIP works
No single receptor for DSIP has been confirmed, which is unusual for a peptide studied this long. It crosses the blood-brain barrier, modulates GABAergic and glutamatergic transmission in the thalamus and brainstem regions that gate slow-wave sleep, and interacts with the opioid and monoamine systems that regulate stress. It also appears to reset cortisol's circadian pattern rather than simply lowering it. Half-life in plasma is minutes, yet sleep-stage effects persist for hours, so it is treated as a signal rather than a sustained-exposure compound. Alongside Selank for anxiety and Semax for attention, it completes the nootropic peptide set.
Specifications
| Compound | DSIP (delta sleep-inducing peptide) |
| Also known as | Emideltide, DSIP peptide, sleep peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu |
| CAS number | 62568-57-4 |
| Molecular formula | C35H48N10O15 |
| Molecular weight | 848.8 g/mol |
| Sequence | WAGGDASGE (9 amino acids) |
| Category | Nootropic and sleep research |
| Purity | ≥99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial size | 10mg |
| Storage (lyophilised) | -20°C, protect from light, avoid freeze-thaw |
| Storage (reconstituted) | 2 to 8°C, use within 28 days |
| Reconstitution | Bacteriostatic water |
Pricing in Australia
$89.99 for 10mg, $9.00 per mg
DSIP is studied in the 100 to 300mcg range per administration, so a 10mg vial covers 30 to 100 draws.
Reconstitution
Wipe the stopper, add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake. Refrigerate at 2 to 8°C and use within 28 days.
| Water added | Concentration | 100mcg on a U-100 syringe | 300mcg on a U-100 syringe |
| 2mL | 5mg/mL | 2 units | 6 units |
| 5mL | 2mg/mL | 5 units | 15 units |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, mass-spec identity against 849 g/mol, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
$79.99. The anxiolytic peptide.
$89.99. For the sleep-phase GH pulse.
From $79.99. Melatonin rhythm research.
10mL $29.99, 3mL $14.99. Required for reconstitution.
DSIP Australia FAQ
What is DSIP?
Delta sleep-inducing peptide, a nine-amino-acid peptide isolated in 1977 from rabbits in slow-wave sleep. It is studied for shifting sleep architecture toward delta sleep, and for cortisol regulation, stress, withdrawal and chronic pain.
Is DSIP a sedative?
No. In research it does not induce sleep on its own; it increases the proportion of slow-wave sleep once asleep, the stage in which GH pulses and memory consolidation occur.
How does DSIP work?
No single receptor is confirmed. It crosses the blood-brain barrier, modulates GABA and glutamate transmission in sleep-gating regions, interacts with opioid and monoamine systems, and resets cortisol's circadian pattern.
What does the research show?
Increased delta sleep and sleep efficiency in animal and small human studies, reduced basal cortisol, reduced withdrawal symptoms in European studies, and lower pain scores in small chronic-pain trials. Evidence is older and mostly small-scale.
DSIP vs Selank?
DSIP is the sleep-architecture peptide; Selank is the daytime anxiolytic. They address different endpoints and are often studied as complementary arms.
Can I buy DSIP at Chemist Warehouse in Australia?
No. DSIP is not a registered medicine and no Australian pharmacy stocks it. It is available only as a research-grade lyophilised vial.
How do you reconstitute DSIP?
Add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake, refrigerate at 2 to 8°C and use within 28 days. 2mL gives 5mg/mL, so 100mcg is 2 units.
Is DSIP available in Australia?
As a research compound, yes: Pure Peptides Australia holds the 10mg vial in Sydney with same-day dispatch. As a medicine, no. As of October 2026 it is not TGA approved.
Where can I buy DSIP in Australia?
From this page. Check out with card, PayID, Osko or bank transfer and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does DSIP cost in Australia?
$89.99 for the 10mg vial, $9.00 per mg. No surcharge on PayID, Osko or bank transfer.
Is DSIP legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
