Pure Peptides Australia
TB-500 โ Research Peptide | Pure Peptides Australia
TB-500 โ Research Peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Tissue repair research compound
TB-500 (10mg): Thymosin Beta-4 Fragment for Cell Migration and Repair Research
TB-500 is the synthetic form of the active region of thymosin beta-4, a 43-amino-acid protein present in almost every cell in the body and the main sequesterer of G-actin, the building block of the cytoskeleton. By holding actin in reserve and releasing it on demand, thymosin beta-4 controls how cells change shape and move, which is why TB-500 is the research peptide for cell migration, angiogenesis and systemic rather than local repair. Searched as tb 500 australia, tb500, thymosin beta 4, tb-500 peptide and tb 500 peptide australia.
Pure Peptides Australia holds TB-500 in Sydney stock as a 10mg lyophilised vial, Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery Australia-wide.
- TB500
- TB 500
- Thymosin beta-4
- Tฮฒ4
- Tbeta4
- Thymosin ฮฒ4 fragment
Local signal or cell supply
Repair needs two things: a signal at the injury and cells arriving to answer it. BPC-157 is studied as the signal, through nitric oxide and growth-factor pathways at the site. TB-500 is studied as the supply, because its LKKTET motif binds actin and lets keratinocytes, fibroblasts and endothelial cells migrate into a wound bed from elsewhere. That division is why the two are paired so consistently, and why the BPC-157 + TB-500 blend exists.
Key research areas
Actin and cell migration
Sequesters monomeric G-actin, releasing it for polymerisation where a cell needs to move. The founding mechanism (Goldstein et al., Expert Opinion on Biological Therapy 2012).
Dermal and corneal wounds
Faster closure and reduced scarring in dermal wound models; corneal epithelial repair and anti-inflammatory activity (Sosne et al., Annals of the New York Academy of Sciences 2010).
Cardiac repair
Studied for cardiomyocyte survival and coronary vessel growth after infarction in animal models, via epicardial progenitor activation.
Tendon and ligament
Studied for tenocyte migration and collagen organisation, often alongside BPC-157 in the same models.
Angiogenesis
Endothelial cell migration, tube formation and new vessel growth, one of thymosin beta-4's best-characterised effects.
Inflammation
Suppression of NF-kB signalling and reduced inflammatory cytokine release during repair.
TB-500 vs thymosin beta-4
Full thymosin beta-4 is 43 amino acids. TB-500 reproduces the actin-binding region (residues 17 to 23, LKKTETQ) that carries the repair-related activity, which is why the two are used almost interchangeably in research writing. The synthetic fragment is more practical to produce and handle than the full protein. Thymosin beta-4 is distinct from Thymosin Alpha-1, an unrelated immune-signalling peptide from the same gland.
Specifications
| Compound | TB-500 (thymosin beta-4 fragment) |
| Also known as | TB500, TB 500, thymosin ฮฒ4, Tฮฒ4, Tbeta4, thymosin beta 4 acetate |
| CAS number | 77591-33-4 (thymosin ฮฒ4) |
| Molecular formula | C212H350N56O78S |
| Molecular weight | 4963.4 g/mol |
| Structure | 43 amino acids, actin-binding LKKTETQ motif |
| Category | Tissue repair research |
| Purity | โฅ99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial size | 10mg |
| Storage (lyophilised) | -20ยฐC, protect from light, avoid freeze-thaw |
| Storage (reconstituted) | 2 to 8ยฐC, use within 28 days |
| Reconstitution | Bacteriostatic water |
Pricing in Australia
$99.99 for 10mg, $10.00 per mg
TB-500 protocols in the literature use a loading phase of larger amounts followed by smaller maintenance draws, so a 10mg vial usually covers one full cycle. Pairing with BPC-157 at 1:1 is simplest through the blend at $109.99 for 5mg of each.
Reconstitution
Wipe the stopper, add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake. Refrigerate at 2 to 8ยฐC and use within 28 days.
| Water added | Concentration | 1mg on a U-100 syringe | 2.5mg on a U-100 syringe |
| 1mL | 10mg/mL | 10 units | 25 units |
| 2mL | 5mg/mL | 20 units | 50 units |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, mass-spec identity against 4963 g/mol, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
From $69.99. The local repair signal to TB-500's cell supply.
From $109.99. Both pre-mixed 1:1.
10mL $29.99, 3mL $14.99. Required for reconstitution.
$139.99. TB-500 with BPC-157 and GHK-Cu in one vial.
TB-500 Australia FAQ
What is TB-500?
The synthetic form of the active region of thymosin beta-4, a protein in nearly every cell that controls actin and therefore how cells move. It is studied for cell migration, angiogenesis and systemic tissue repair.
Is TB-500 the same as thymosin beta-4?
TB-500 reproduces the actin-binding region (residues 17 to 23) of the full 43-amino-acid protein that carries the repair activity, so the two are used almost interchangeably in research writing.
How does TB-500 work?
It sequesters G-actin and releases it where a cell needs to build cytoskeleton, letting cells migrate into damaged tissue. It also promotes endothelial tube formation and damps NF-kB inflammatory signalling.
What does the research show?
Faster dermal and corneal wound closure with less scarring, cardiomyocyte survival and vessel growth after infarction in animal models, and tenocyte migration in tendon models. All preclinical or early-phase.
TB-500 or BPC-157?
TB-500 for cell migration and systemic repair; BPC-157 for the localised signal and the gut. Most protocols use both, hence the blend.
Can I buy TB-500 at Chemist Warehouse in Australia?
No. TB-500 is not a registered medicine and no Australian pharmacy stocks it. It is available only as a research-grade lyophilised vial.
How do you reconstitute TB-500?
Add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake, refrigerate at 2 to 8ยฐC and use within 28 days. 2mL gives 5mg/mL, so 1mg is 20 units on a U-100 syringe.
Is TB-500 available in Australia?
As a research compound, yes: Pure Peptides Australia holds the 10mg vial in Sydney with same-day dispatch. As a medicine, no. As of October 2026 it is not TGA approved.
Where can I buy TB-500 in Australia?
From this page. Check out with card, PayID, Osko or bank transfer and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does TB-500 cost in Australia?
$99.99 for the 10mg vial, $10.00 per mg. No surcharge on PayID, Osko or bank transfer.
Is TB-500 legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
