Pure Peptides Australia
Thymosin Alpha-1 (Tα1) 10mg- Research peptide | Pure Peptides Australia
Thymosin Alpha-1 (Tα1) 10mg- Research peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Immune research compound
Thymosin Alpha-1 (10mg): The Immune-Modulating Thymic Peptide
Thymosin Alpha-1, Tα1, is a 28-amino-acid acetylated peptide first isolated from thymus tissue in 1977 and later identified as the N-terminal fragment of prothymosin alpha. It is the most studied immune-modulating peptide in existence, with over four decades of trials as thymalfasin in hepatitis B and C, sepsis, cancer adjuvant therapy and vaccine response, and it is approved as a medicine in more than thirty countries. Searched as thymosin alpha 1 australia, ta1 peptide, thymalfasin, zadaxin and thymosin alpha-1 immune.
Pure Peptides Australia holds Thymosin Alpha-1 in Sydney stock as a 10mg lyophilised vial, Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery Australia-wide.
- Thymosin Alpha-1
- Tα1
- TA1
- Thymalfasin
- Zadaxin (brand)
- Prothymosin alpha 2-29
Not the same as TB-500
The two thymosins are unrelated in structure and function. TB-500 is thymosin beta-4, an actin-binding protein studied for cell migration and tissue repair. Thymosin Alpha-1 is a signalling peptide that acts on immune cells through Toll-like receptors, studied for immune restoration and antiviral response. They share a name because both were first isolated from thymus extract; that is the extent of the connection.
Key research areas
Chronic hepatitis B and C
Thymalfasin trials reported improved viral clearance alone and with interferon, the basis of its approvals (Chien et al., Hepatology 1998).
Sepsis
Reduced 28-day mortality in a large Chinese sepsis trial (Wu et al., Critical Care 2013), one of the few positive immunomodulator results in that setting.
Cancer adjuvant
Studied alongside chemotherapy in melanoma, lung and hepatocellular carcinoma for immune recovery and survival.
Vaccine response
Increased antibody titres after influenza vaccination in older and immunocompromised subjects.
T-cell maturation
Promotes differentiation of thymocytes into mature T cells and increases CD4 and CD8 populations.
Respiratory viral infection
Studied in COVID-19 cohorts for T-cell recovery and reduced mortality in early observational work.
How Thymosin Alpha-1 works
Tα1 binds Toll-like receptors 2 and 9 on dendritic cells and other antigen-presenting cells, driving them toward a mature, antigen-presenting state and increasing interleukin-2, interferon-gamma and the T-helper 1 response. It also raises natural killer cell activity and, in the thymus, promotes thymocyte maturation. Crucially it modulates rather than simply stimulates: in inflammatory settings it has been reported to lower excessive cytokine release, which is why it is studied in sepsis as well as in immune deficiency. Half-life is about two hours.
Specifications
| Compound | Thymosin Alpha-1 (Tα1) |
| Also known as | TA1, thymalfasin, Zadaxin (brand), prothymosin alpha 2-29, N-acetyl thymosin alpha 1 |
| CAS number | 62304-98-7 |
| Molecular formula | C129H215N33O55 |
| Molecular weight | 3108.3 g/mol |
| Structure | 28 amino acids, N-terminal acetylation |
| Half-life (published) | Approximately 2 hours |
| Category | Immune research |
| Purity | ≥99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial size | 10mg |
| Storage (lyophilised) | -20°C, protect from light, avoid freeze-thaw |
| Storage (reconstituted) | 2 to 8°C, use within 28 days |
| Reconstitution | Bacteriostatic water |
Pricing in Australia
$89.99 for 10mg, $9.00 per mg
The thymalfasin trials used 1.6mg twice weekly, so a 10mg vial covers three weeks of a trial-pattern arm.
Reconstitution
Wipe the stopper, add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake. Refrigerate at 2 to 8°C and use within 28 days.
| Water added | Concentration | 1mg on a U-100 syringe | 1.6mg on a U-100 syringe |
| 2mL | 5mg/mL | 20 units | 32 units |
| 1mL | 10mg/mL | 10 units | 16 units |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, mass-spec identity against 3108 g/mol, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
$79.99. The anti-inflammatory counterpart.
$99.99. The other thymosin, for repair research.
$159.99. Lymphocyte redox research alongside.
10mL $29.99, 3mL $14.99. Required for reconstitution.
Thymosin Alpha-1 Australia FAQ
What is Thymosin Alpha-1?
A 28-amino-acid acetylated thymic peptide, the most studied immune modulator in the peptide field, with four decades of trials as thymalfasin in hepatitis, sepsis, cancer adjuvant therapy and vaccine response.
Thymosin Alpha-1 vs TB-500?
Unrelated. TB-500 is thymosin beta-4, an actin-binding repair peptide. Thymosin Alpha-1 is an immune signalling peptide acting through Toll-like receptors. They share a name because both came from thymus extract.
How does Thymosin Alpha-1 work?
It binds TLR2 and TLR9 on dendritic cells, driving maturation and a T-helper 1 response, raises natural killer activity and promotes T-cell maturation in the thymus. It modulates rather than simply stimulates, lowering excessive cytokines in inflammatory settings.
What does the research show?
Improved viral clearance in hepatitis B and C trials, reduced 28-day mortality in a large sepsis trial, increased vaccine antibody titres in older subjects, and immune recovery alongside chemotherapy. Approved as thymalfasin in over thirty countries.
Can I buy Thymosin Alpha-1 at Chemist Warehouse in Australia?
No. Thymalfasin is not registered in Australia and research-grade Thymosin Alpha-1 is not a pharmacy product. It is available only as a research-grade lyophilised vial.
How do you reconstitute Thymosin Alpha-1?
Add bacteriostatic water slowly down the inside wall, swirl gently until clear, never shake, refrigerate at 2 to 8°C and use within 28 days. 2mL gives 5mg/mL, so 1.6mg is 32 units.
Is Thymosin Alpha-1 available in Australia?
As a research compound, yes: Pure Peptides Australia holds the 10mg vial in Sydney with same-day dispatch. As a medicine, no. As of October 2026 it is not TGA approved.
Where can I buy Thymosin Alpha-1 in Australia?
From this page. Check out with card, PayID, Osko or bank transfer and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does Thymosin Alpha-1 cost in Australia?
$89.99 for the 10mg vial, $9.00 per mg. No surcharge on PayID, Osko or bank transfer.
Is Thymosin Alpha-1 legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. It is not approved by the TGA for human or veterinary use and is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
