Pure Peptides Australia
Tirzepatide 10mg โ Research Peptide | Pure Peptides Australia
Tirzepatide 10mg โ Research Peptide | Pure Peptides Australia
Not for human, veterinary, diagnostic, or therapeutic use.
Metabolic research compound
Tirzepatide (10mg): Dual GIP and GLP-1 Receptor Agonist Research Peptide
Tirzepatide is a 39-amino-acid synthetic peptide developed by Eli Lilly under the code LY3298176 and the first dual incretin agonist to reach the market overseas. It activates both the GIP and GLP-1 receptors from a single molecule, and it is the compound most researchers use as the reference arm when studying Retatrutide and other next-generation metabolic peptides. Searched as tirzepatide peptide australia, tirz, tirzep, tirzepatide 10mg and by its brand names Mounjaro and Zepbound.
Pure Peptides Australia holds Tirzepatide in Sydney stock as a 10mg lyophilised vial, Janoshik tested before listing. Orders confirmed before 12pm AEST on a business day are dispatched the same day with tracked delivery to every state and territory.
- Tirzepatide
- Tirz
- Tirzep
- LY3298176
- Dual GIP/GLP-1 agonist
- Mounjaro (brand)
Where it sits in the class
Semaglutide activates one receptor, GLP-1. Tirzepatide activates two, adding GIP. Retatrutide activates three, adding glucagon. Tirzepatide has the longest and broadest research record of the three, with the SURPASS diabetes programme and SURMOUNT obesity programme spanning tens of thousands of participants, which is why it is the benchmark newer compounds are measured against.
Key research areas
Body-weight regulation
SURMOUNT-1 (Jastreboff et al., NEJM 2022, n=2,539, 72 weeks): 15.0%, 19.5% and 20.9% mean weight reduction at 5mg, 10mg and 15mg weekly against 3.1% for placebo.
Glycaemic control
The SURPASS 1 to 5 programme in type 2 diabetes reported HbA1c reductions of 1.9 to 2.6 points, outperforming semaglutide 1mg head to head in SURPASS-2 (Frias et al., NEJM 2021).
Dual incretin pharmacology
Studied for how GIP activity adds to GLP-1: additive weight effects, improved insulin sensitivity and reduced nausea at a given level of GLP-1 stimulation.
Cardiovascular outcomes
SURPASS-CVOT compared Tirzepatide against dulaglutide on major adverse cardiac events, and SUMMIT examined heart failure with preserved ejection fraction.
Sleep apnoea and liver
SURMOUNT-OSA reported reduced apnoea-hypopnoea index; SYNERGY-NASH examined liver histology in metabolic-associated steatohepatitis.
Comparison arm
In-vitro and comparative work uses Tirzepatide as the dual-agonist control against Retatrutide's triple agonism and semaglutide's single agonism.
How Tirzepatide works
Tirzepatide is built on a GIP backbone with substitutions that add GLP-1 receptor activity, and it carries a C20 fatty diacid on a lysine side chain that binds serum albumin, giving a plasma half-life of about five days. GLP-1 receptor activity slows gastric emptying, reduces food intake and increases glucose-dependent insulin release. GIP receptor activity is studied for adding to those effects on weight and insulin sensitivity while moderating the nausea that pure GLP-1 agonists produce. Its GIP affinity is close to native GIP; its GLP-1 affinity is roughly five-fold weaker than native GLP-1, a deliberate imbalance.
Against Retatrutide, Tirzepatide's highest arm reached 20.9% at 72 weeks in SURMOUNT-1 versus 28.3% at 80 weeks in TRIUMPH-1, in different trials. Tirzepatide has the longer record; Retatrutide the larger effect. Both are stocked here so comparison arms can run from one order.
Specifications
| Compound | Tirzepatide (LY3298176) |
| Also known as | Tirz, tirzep, tirzepatide peptide, dual GIP/GLP-1 agonist, twincretin; brand names Mounjaro, Zepbound |
| CAS number | 2023788-19-2 |
| Molecular formula | C225H348N48O68 |
| Molecular weight | 4813.5 g/mol |
| Structure | 39 amino acids on a GIP backbone, C20 fatty diacid lipidation |
| Half-life (published) | Approximately 5 days |
| Category | Metabolic research |
| Purity | โฅ99% HPLC, batch COA supplied (Janoshik Analytical) |
| Form | Lyophilised powder in a sealed sterile vial |
| Vial size | 10mg |
| Storage (lyophilised) | -20ยฐC long term, 2 to 8ยฐC short term, protect from light |
| Storage (reconstituted) | 2 to 8ยฐC, use within 28 days |
| Reconstitution | Bacteriostatic water |
Pricing in Australia
$119.99 for 10mg, $12.00 per mg
A 10mg vial yields ten 1mg aliquots or four 2.5mg aliquots. For reference, the SURMOUNT arms were 5mg, 10mg and 15mg weekly after a stepped start from 2.5mg, which describes the sponsor's controlled trials of a pharmaceutical-grade product. Researchers comparing dual and triple agonism pair this vial with a Retatrutide 10mg at $159.99.
Reconstitution
Wipe the stopper, draw bacteriostatic water and run it slowly down the inside wall of the vial rather than onto the powder. Swirl gently until clear, never shake. Refrigerate at 2 to 8ยฐC and use within 28 days.
| Water added | Concentration | 1mg on a U-100 syringe | 2.5mg on a U-100 syringe |
| 1mL | 10mg/mL | 10 units | 25 units |
| 2mL | 5mg/mL | 20 units | 50 units |
| 3mL | 3.33mg/mL | 30 units | 75 units |
The reconstitution calculator runs the maths for any target.
Quality and COA verification
Every batch is tested by Janoshik Analytical: HPLC purity, mass-spec identity against 4813 g/mol, heavy metals and endotoxin. The batch number on the label matches the certificate.
Sydney stock, tracked delivery
No international transit or customs queue. Orders cleared before 12pm AEST leave the same business day; Express Post reaches most metro addresses in one to three business days.
Frequently bought together
$159.99. The triple-agonist comparison arm.
10mL $29.99, 3mL $14.99. Required for reconstitution.
$149.99. The amylin analogue studied alongside incretin agonists.
5 pack $15.99, 10 pack $19.99.
Tirzepatide Australia FAQ
What is Tirzepatide?
A 39-amino-acid synthetic peptide developed by Eli Lilly (LY3298176) that activates the GIP and GLP-1 receptors together. It is the first dual incretin agonist to reach market overseas and the reference compound for newer metabolic peptides.
What is Tirzepatide also known as?
Tirz, tirzep, tirzepatide peptide, LY3298176 and twincretin. Overseas it is marketed as Mounjaro and Zepbound; this listing is the research-grade lyophilised compound, not a branded pen.
How does Tirzepatide work?
GLP-1 activity slows gastric emptying, reduces food intake and increases glucose-dependent insulin release. GIP activity is studied for adding to those effects while moderating nausea. A C20 fatty diacid binds albumin for a five-day half-life.
What does the research show?
SURMOUNT-1 reported 20.9% weight reduction at 15mg over 72 weeks. SURPASS-2 reported greater HbA1c reduction than semaglutide 1mg. Further trials cover cardiovascular outcomes, heart failure, sleep apnoea and liver histology. These describe controlled trials of a pharmaceutical-grade product.
Tirzepatide vs Retatrutide: what is the difference?
Tirzepatide acts on two receptors, Retatrutide on three. Tirzepatide's highest arm reached 20.9% at 72 weeks; Retatrutide's reached 28.3% at 80 weeks, in different trials. Tirzepatide has the longer research record and the approved-product history overseas.
Tirzepatide vs semaglutide?
Semaglutide is GLP-1 only. In the SURPASS-2 head-to-head, Tirzepatide produced larger HbA1c and weight reductions than semaglutide 1mg. The GIP component is the difference.
Can I buy Tirzepatide at Chemist Warehouse in Australia?
Pharmacies dispense the branded Mounjaro pen on prescription. This listing is the research-grade lyophilised compound, which is not a pharmacy product and is supplied for laboratory use only.
How do you reconstitute Tirzepatide?
Add bacteriostatic water slowly down the inside wall of the vial, swirl gently until clear, never shake, refrigerate at 2 to 8ยฐC and use within 28 days. 2mL gives 5mg/mL, so 1mg is 20 units on a U-100 syringe.
How should Tirzepatide be stored?
Lyophilised at -20ยฐC long term or 2 to 8ยฐC short term, away from light. Reconstituted at 2 to 8ยฐC and used within 28 days.
Is Tirzepatide available in Australia?
As a research compound, yes: Pure Peptides Australia holds the 10mg vial in Sydney with same-day dispatch. The branded pen is a separate, prescription-only product.
Where can I buy Tirzepatide in Australia?
From this page. Check out with card, PayID, Osko or bank transfer and the vial leaves Sydney the same business day when payment clears before 12pm AEST, tracked to any Australian address.
What does Tirzepatide cost in Australia?
$119.99 for the 10mg research vial, $12.00 per mg. No surcharge on PayID, Osko or bank transfer.
Is Tirzepatide legal in Australia?
Pure Peptides Australia supplies it strictly for lawful in-vitro laboratory research. The research-grade compound is not sold as a medicine, supplement or therapeutic good. Purchasers are responsible for ensuring their use complies with applicable laws.
